A groundbreaking study has revealed that harmful bacteria and fungi living in the mouth may significantly raise the risk of developing one of the deadliest forms of cancer—pancreatic cancer.
Oral Bacteria and Cancer: The Connection
For years, experts have suspected that poor oral hygiene can increase vulnerability to serious health issues, including cancer. Now, researchers from NYU School of Medicine have identified specific microbes in the mouth that may triple the risk of pancreatic cancer.
The theory is that these harmful microbes can travel from the mouth to the pancreas via saliva, potentially triggering disease.
Dr. Richard Hayes, population health expert and co-author of the study published in JAMA Oncology, explained:
“It is clearer than ever that brushing and flossing your teeth may not only help prevent periodontal disease but may also protect against cancer.”
The Role of the Oral Microbiome
The “oral microbiome”—the diverse community of bacteria and fungi in the mouth—is under increasing scientific scrutiny.
This latest study is the largest of its kind, analysing saliva samples from 900 participants in two long-term U.S. health studies. Researchers tracked participants for around nine years, comparing the oral microbiome of 445 pancreatic cancer patients with 445 cancer-free individuals.
Key findings included:
-
24 species of bacteria and fungi were linked to changes in pancreatic cancer risk.
-
A type of yeast called candida, normally present in the body, was identified as a potential risk factor.
-
Several bacteria already linked to gum disease (periodontitis) were also connected to higher cancer risk.
Altogether, this group of harmful microbes increased the likelihood of developing pancreatic cancer more than threefold.
A Potential Tool for Cancer Risk Screening
By analysing bacterial and fungal DNA from saliva samples, researchers created a risk assessment tool that could one day help doctors identify individuals who may need earlier screening for pancreatic cancer.
Professor Jiyoung Ahn, co-author of the study, noted:
“By profiling bacterial and fungal populations in the mouth, oncologists may be able to flag those most in need of pancreatic cancer screening.”
Why This Matters
Pancreatic cancer is often called the “silent killer” because its symptoms are subtle and often mistaken for less serious conditions. Unfortunately, it remains one of the least survivable cancers:
-
Around 10,000 deaths occur each year in the UK, roughly one every hour.
-
By 2040, cases are expected to rise dramatically, with an estimated 201,000 diagnoses worldwide.
-
When caught early, about half of patients survive a year or more. But when diagnosed late—after it has spread—only 1 in 10 patients survive.
Reach Waxed Dental Floss for Plaque and Food Removal, Refreshing Mint Flavor, 200 Yards
Symptoms to Watch For
While most symptoms are not caused by cancer, experts urge people to get checked by a GP if they persist for more than four weeks. Warning signs include:
-
Jaundice (yellowing of the skin and eyes)
-
Itchy skin and dark urine
-
Loss of appetite and unexplained weight loss
-
Bloating or constipation
Lifestyle Risks
According to Cancer Research UK, lifestyle factors play a major role:
-
22% of pancreatic cancer cases are linked to smoking (which also promotes gum disease).
-
12% are linked to obesity.
Interestingly, cases have surged among young women under 25, with rates increasing by up to 200% since the 1990s—though oncologists remain puzzled as to why.
The Takeaway
This research highlights a crucial message: oral health isn’t just about teeth and gums—it could also be a key factor in cancer prevention. Maintaining good oral hygiene through brushing, flossing, and regular dental check-ups may provide protection well beyond the mouth.
👉 Tip for readers: If you’ve experienced any of the symptoms listed above or have concerns about your risk, consult your doctor promptly. And don’t underestimate the power of a toothbrush—it could be protecting more than just your smile.
Comments
Post a Comment